>be amino acid sequence
>have up to 20^30 combinations of protein shapes
>somehow choose the right one
>no one knows how it happens
>just suppose to take it at face value
They just rearrange themselves and boom magic happens
>be amino acid sequence. >have up to 20^30 combinations of protein shapes. >somehow choose the right one
Falling into your wing while paragliding is called 'gift wrapping' and turns you into a dirt torpedo pic.twitter.com/oQFKsVISkI
— Mental Videos (@MentalVids) March 15, 2023
>be belief
>infect the mind of retards without evidence
but muh authority figure says it's true so it's impossible that he could lie!!!
Proteins are fucking magic.
Viruses are just tricky proteins.
Mad Cow/Creutzfeldt-Jakob Disease? Proteins.
Slim Jims? Proteins.
Admit it, proteins are scary, unknown, and powerful.
>somehow
ermm proteins are not just sqn there are a lot more bonds involved with it and it always ends up being the most optimal one. its still a fascinating subject though. if youre interested in protein structures you should try the puzzle game FoldIt
Im trying to explain it the best way possible and this article could probably explain it better :https://en.m.wikipedia.org/wiki/Levinthal%27s_paradox
Lot of stuff they teach you in school is like this . Memorize formulas and facts then gouge them out on a test while not thinking about it what you been taught is actually factual and how it works .
Funny thing is that you need proteins to make proteins so you have a chicken or the egg experiment.
Chicken? Protein.
Egg? Protein.
i get where youre coming from but
>1969
there have been very interesting discoveries about not only protein folding but also aminoacid sequencing after those times. hell even pcr was after that.
But they still havent explained it they do have AI that can predict what protein fold youll get from a sequence but at most theyre 90% accurate and they dont understand how it figured it out .
give it some more years maybe theyll make snother ai that can translate what it means lol. its just one of the ways naturally, things go in the most efficient way possible.
How can you wrap your head around this that a bunch of unalive molecules arrange themselves within few milliseconds to make right structure and how tf do heat proteins come into play .
Because there's some most stable equilibrium shape based on the underlying physics and chemistry where the net forces encouraging it to move any further in any given direction are zero
this
and i study bioengineering and if i dont act like i know even a little bit i crap my pants a little because im really afraid to fail a class. i genuinely study though aha ha
First year bio student also planning to do computational biology and go into biotech or medschool. anon any recommendations to be a better student and get laid . But Id rather have a career then get pussy
So it comes down to minor chemical reactions and bonds that end up making the shape . The whole protein folding thing is so hard to comprehend. You think you got it then few moments later you realize you know shit
idk i never went on a date ever but
>be autistic about your major
>take concerta
>make studying your hobby
>consume content about bio (like i said you should check out foldit)
you csn also try signing up for independent classes. most unis hold study camps during breaks including laboratory sessions which are very good for cv and learning ahead of the curriculum, and getting more handson experience early on. i always daydream about attending one and even finding a friend there.
>im probably autistic since I lack a social life and always been the loner .
>should I really get on adderal train ?
>I have no hobbies so ill try
>like movies and documentaries?
Plz recommend some too
i meant like hyperfixate on biology.
>aderall
i never tried that, if you think your dopamine receptors are fine and can study without it, dont take it. if youre just a slouch try takig modafinil.
>movies and documentaries
i find those boring so i generally watch youtube or read books but generally articles/magazines.
>id rather not use drugs lol but with the way my life is heading I might
>give me some YouTube kino anon
go on chubbyemu and plainlydifficult and subscribr to them and all the reccomended channels. soon an MIT lecture about neuroscience/psychology will appear on your reccomended. watch it but dont like comment or subscribe. your algorithm will now cater towards biokino
Ur a good fren would u mind dropping your discord?
sure haaha tentacleTherapist#8569
added u anon thx
This will start clicking with more classes especially since they have a lot of overlap and review
>the right structure
Protein folding isn't perfect or "right". Like with most things in life, young people are taught using a deterministic model, but the reality is highly probabilistic.
Some proteins are small enough to be consistent in how they fold and interact with their environment, but most of the time they are fluid. Behaviors at the molecular scale don't have any analog to what makes logical sense to us.
We know a little.
(1) Thermodynamics of protein chain synthesis: we have evidence of codon changes that are synonymous: there is no amino acid change despite the mutation but it still produces dysfunctional proteins in cancers. The only difference is the codon frequency: one being more common than the other in terms of anti-codons.
(2) Several highly preserved regions that just click because it worked once million years ago. All other proteins are just derivatives of tried designs.
(3) Chaperones and heat shock proteins.
This doesn't account for much, but it is something.
what's fuckin whack too is how the actual primary code doesn't seem to matter as much as the shape when looking at proteins that do the same thing in different species. How the fuck does that work? Nobody knows.
The primary structure affects the local secondary structure. The secondary structure affects other secondary structure to form the tertiary, true 3D structure. And then multiple tertiary structures can combine into a quaternary structure if it has several subunits.
Very subtle changes in the primary code and how subunits combine mean the difference between a fatty acid desaturase in humans and a lipid-based pheromone enzyme in moths. Really the same deal but ours is specific for fatty acids while the moths take different fatty acids to make their pheromones.
>primary code doesnt matter
it does thpugh.. and forms codones... and stuff..
>Imagine being this scientifically illiterate
Anon you could have done a 5-10 min search instead of announcing to everyone that you're an idiot
>le Redditor who thinks hes so smart
Congrats on your useless biology courses guys now please shut the fuck up
Did you just crash some random person's house party just to tell everyone to pack it up and go home?
If they gay, yeah
>Largest molecule which could have even the slightest chance of reproducing itself is like 80+ amino acids long
>The chance of such a molecule appearing by chance is like 1 in 10^1200
Either god exists or the universe is way bigger than the observable universe.