- This topic has 22 replies, 1 voice, and was last updated 1 year, 4 months ago by
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What will happen once penicillin stops being effective?
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We either start using antimicrobials more carefully and rationally, or repeat the fate of penicillin with other antibiotics.
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this.
though we’ll probably come up with some organo-metalic forms of treatment.
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I’ve heard my CPU is capable of being antibiotics.
Just don’t tell anybody, they will deconstruct the botnet in event of microbial dissease.
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>We either start using antimicrobials more carefully and rationally,
there is a big push in many countries doing exactly that with antibiotic stewardship programmes.
>or repeat the fate of penicillin with other antibiotics.
Unfortunately the fate of penicillin not working where it once did has happened to virtually every other antibiotic in existence also.
>plague pandemic
Even the plague epidemics in the 1800-1900s never reached those figures and this was in an era before penicillin. People know far more about sanitation, hygiene, and infection control now than then so the casualty rates should be far lower even without penicillin.
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an epidemic with even 5% mortality would be apocalyptically bad
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Not really. We’re literal millennia away from being specialized enough for even a 50% reduction in humanity being meaningful from an economic standpoint.
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we get a plague pandemic with 30-50% fatality rates
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That’s already happened
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This
There are so many antibiotics that are completely worthless now tbh.
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Breed new penincilins by exposing fungus to bacteria and watch them duke it out.
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is using viruses to fight bacteria a popsci meme or actually feasible?
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Right now? Popsci
Feasible in the long-term future? Maybe -
apparently you need to go to east Europe. (Georgia is strong there i think).
antibiotics were developed during the cold war so the east went full phage.they take a sample of you’re bacterial infection send it in a lab and search a appropriate phage for it.
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Feasable with mRNA. Its literally rewriting virus to fight against certain strains.
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The use of bacteriophages to treat infections is almost (if not older) than that of modren antibiotics but fell out of favour in the west sometime in the 60s/70s if I recall correctly. Former soviet countries practiced it far longer and in some still do but there are limitation to phage therapy too.
One interesting modern example of phage therapy making a comeback in the West was the use of a phage cocktail applied to Cf patients dressings of a wound infected with a very drug resistant mycobacterial strain.
Feasable with mRNA. Its literally rewriting virus to fight against certain strains.
Bacteriophages exist in nature already.
>Why do we not just always use three+ different antibiotics operating under different mechanisms at once?
Side effects, route of administration (not all can be taken orally or have optimum efficacy if done so, costs of taking a cocktail of drugs instead of one targeted one. These are just a few I can think of.
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2019 year ~20000 people died from MRSA in German hospitals.
covid only got 33000.-
Covid was discovered in december.
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Already happened.
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the 1980s
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Methylicin
Methylated LSD is highest grade antibiotics.
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The real question is why since scrotes have started to deliberately produce anti-biotic resistant strains have we continued to prescribe single antibiotics on an outpatient level, beyond the obvious answer of "not every nation would institute such a policy, so it would ultimately be pointless and only harmful to nations that did so"?
Why do we not just always use three+ different antibiotics operating under different mechanisms at once? The odds of a bacteria developing immunity to three+ different antibiotics at once should be stupidly low, right? -
Realistically, it will be very bad
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